In the first 25 years of its existence, the VIVIT has published over 450 articles. The results of this work are regularly presented in talks at national and international meetings. Many of these publications and presentations have been acknowledged as significant scientific contributions and gained recognition both, nationally and internationally. In the field of cardiovascular disease and diabetes mellitus research, the VIVIT is one of the most active research institutes in Austria and has its place amongst Europe’s top institutes.
Quercetin is a regulator of genes associated with type 2 diabetes
Quercetin results from the oxidation of a plant-based pigment and is found in many fruits and vegetables such as capers, onions, cherries, blueberries, bananas, and in herbs such as lovage. Experiments conducted by the team of the VIVIT molecular biology laboratory showed that quercetin affects the oxygen supply to adipocytes and, as a consequence, the regulation of genes that govern metabolism and energy budget. In human adipocytes, the expression of metabolism genes which promote the emergence of metabolic diseases such as type 2 diabetes, could be downregulated by quercetin.
Quercetin: Nutrients, 2016 May 12;8(5)MORE INFO
Real-time PCR based HLA-B*27 screening directly in whole blood
Geiger K, Zach C, Leiherer A, Fraunberger P, Drexel H, Muendlein A
HLA. 2019 Nov 20. doi: 10.1111/tan.13767
Serotonin is elevated in risk-genotype carriers of TCF7L2 - rs7903146
Leiherer A, Muendlein A, Saely CH, Fraunberger P, Drexel H
Sci Rep. 2019 Sep 6;9(1):12863. doi: 10.1038/s41598-019-49347-y
Unrecognized High Occurrence of Genetically Confirmed Hereditary Carnitine Palmitoyltransferase II Deficiency in an Austrian Family Points to the Ongoing Underdiagnosis of the Disease
Zach C, Unterkofler K, Fraunberger P, Drexel H, Muendlein A
Front Genet. 2019 May 22;10:497. doi: 10.3389/fgene.2019.00497. eCollection 2019
The novel adipokine CTRP1 is significantly associated with the incidence of major adverse cardiovascular events
Muendlein A, Leiherer A, Saely C, Ebner J, Geiger K, Brandtner EM, Vonbank A, Fraunberger P, Drexel H
Atherosclerosis. 2019 Jul;286:1-6. doi: 10.1016/j.atherosclerosis.2019.04.222. Epub 2019 Apr 20
Diabetes Awareness Among Coronary Artery Disease Patients Is Higher in Women Than in Men.
Saely CH, Mader A, Heinzle CF, Zanolin-Purin D, Larcher B, Vonbank A, Drexel H